已入深夜,您辛苦了!由于当前在线用户较少,发布求助请尽量完整的填写文献信息,科研通机器人24小时在线,伴您度过漫漫科研夜!祝你早点完成任务,早点休息,好梦!

Etiologies and Outcomes of Spinal Epidural Lipomatosis

医学 病因学 逻辑回归 腰骶关节 疾病 队列 肥胖 脂肪增多症 儿科 外科 内科学
作者
Safwan Alomari,Daniel Lubelski,Jawad M. Khalifeh,Amanda N. Sacino,Nicholas Theodore,Timothy F. Witham,Ali Bydon
出处
期刊:Clinical spine surgery [Ovid Technologies (Wolters Kluwer)]
卷期号:35 (9): 383-387 被引量:7
标识
DOI:10.1097/bsd.0000000000001344
摘要

This was a systematic review of the literature.The aim was to examine the contemporary demographics, etiological factors, treatment options and outcomes of spinal epidural lipomatosis (SEL) in adults.SEL is primarily seen in obese patients as well as those on steroid therapy. Much regarding the etiology and treatment outcomes of SEL is unknown.We reviewed Ovid MEDLINE, PubMed, SCOPUS, and Google Scholars databases from 1990 through August 2020 to identify cases of SEL. Data collected included patient characteristics, disease associations, level of pathology, treatment, and clinical outcomes.Ninety articles (145 individual cases) were included in the analysis. The median age was 54 years and 79% were males. Obesity-associated SEL constituted the largest proportion (52%) of our cohort. 22% of SEL cases were related to steroid use, while 26% cases were considered to be idiopathic. Lumbosacral SEL was the most frequently reported level of disease (68.9%), followed by the thoracic level (26.2%). The mean age of cases who underwent surgical intervention was 55 years, as compared with 48 years in those who received conservative management ( P =0.03). 95% of patients reported some degree of symptomatic improvement regardless of the treatment modality. Logistic regression suggested a possible superior outcome associated with those undergoing surgical treatment.In contrast to historical comparisons, contemporary articles support that obesity has become the major contributing factor for SEL. Logistic regression of the existing cases suggests that there may be a role for surgical intervention in select patients.
最长约 10秒,即可获得该文献文件

科研通智能强力驱动
Strongly Powered by AbleSci AI
更新
大幅提高文件上传限制,最高150M (2024-4-1)

科研通是完全免费的文献互助平台,具备全网最快的应助速度,最高的求助完成率。 对每一个文献求助,科研通都将尽心尽力,给求助人一个满意的交代。
实时播报
刚刚
灵巧的白山完成签到,获得积分10
1秒前
魔法师完成签到,获得积分10
2秒前
DAKE发布了新的文献求助10
2秒前
3秒前
frap发布了新的文献求助10
3秒前
3秒前
CNSer发布了新的文献求助10
5秒前
NexusExplorer应助小北采纳,获得10
5秒前
科研美少女完成签到 ,获得积分10
5秒前
7秒前
小佛爱学护理学完成签到,获得积分10
7秒前
8秒前
蒋龙发布了新的文献求助10
8秒前
9秒前
9秒前
宇智波白哉完成签到 ,获得积分10
9秒前
9秒前
Youngman完成签到,获得积分10
10秒前
up关闭了up文献求助
11秒前
12秒前
赘婿应助小中采纳,获得10
13秒前
yiyi131发布了新的文献求助10
13秒前
隐形曼青应助星星采纳,获得10
14秒前
17秒前
lyc发布了新的文献求助10
17秒前
星辰大海应助Hana采纳,获得10
19秒前
20秒前
郁金香发布了新的文献求助10
21秒前
深情安青应助科研通管家采纳,获得10
21秒前
研友_VZG7GZ应助科研通管家采纳,获得10
21秒前
21秒前
21秒前
Lucas应助科研通管家采纳,获得10
21秒前
21秒前
21秒前
ding应助科研通管家采纳,获得10
21秒前
25秒前
晓晓来了发布了新的文献求助10
26秒前
冲塔亚德发布了新的文献求助10
26秒前
高分求助中
The Young builders of New china : the visit of the delegation of the WFDY to the Chinese People's Republic 1000
юрские динозавры восточного забайкалья 800
English Wealden Fossils 700
Chen Hansheng: China’s Last Romantic Revolutionary 500
宽禁带半导体紫外光电探测器 388
COSMETIC DERMATOLOGY & SKINCARE PRACTICE 388
Case Research: The Case Writing Process 300
热门求助领域 (近24小时)
化学 医学 生物 材料科学 工程类 有机化学 生物化学 物理 内科学 纳米技术 计算机科学 化学工程 复合材料 基因 遗传学 催化作用 物理化学 免疫学 量子力学 细胞生物学
热门帖子
关注 科研通微信公众号,转发送积分 3142265
求助须知:如何正确求助?哪些是违规求助? 2793200
关于积分的说明 7805849
捐赠科研通 2449486
什么是DOI,文献DOI怎么找? 1303333
科研通“疑难数据库(出版商)”最低求助积分说明 626823
版权声明 601291