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Impact of allergic rhinitis control on work productivity and costs: a real-world data MASK-air study

医学 呈现主义 旷工 间接成本 生产力 哮喘 工作效率 过敏 百分位 物理疗法 内科学 免疫学 宏观经济学 业务 经济 管理 会计 统计 数学
作者
Rafael José Vieira,Luís Filipe Azevedo,Ana Margarida Pereira,Diogo Nogueira-Leite,Francisco Rocha Gonçalves,Désirée Larenas‐Linnemann,Álvaro A. Cruz,Bilun Gemicioğlu,Bolesław Samoliński,Leticia de las Vecillas,Mattia Giovannini,Maria João Cunha,Jorge Rodrigues,Violeta Kvedarienė,Ludger Klimek,Oliver Pfaar,Torsten Zuberbier,João Fonseca,Jean Bousquet,Bernardo Sousa‐Pinto
出处
期刊:The Journal of Allergy and Clinical Immunology: In Practice [Elsevier BV]
卷期号:12 (11): 3107-3115.e13 被引量:1
标识
DOI:10.1016/j.jaip.2024.07.026
摘要

Background Allergic rhinitis (AR) has a substantial socioeconomic impact associated with impaired work productivity. Objective To study the impact of AR on work productivity and estimate the corresponding indirect costs for 40 countries. Methods We conducted a cross-sectional study using direct patient data from the MASK-air® app on users with self-reported AR. We used the Work Productivity and Activity Impairment Questionnaire: Allergy Specific to measure the impact of AR on work productivity (presenteeism and absenteeism). Weekly indirect costs were estimated per country, for each level of rhinitis control and considering patients with and without asthma. Results We assessed data from 677 weeks (364 patients), 280 of which were reported by patients with asthma. Regarding presenteeism, the median impact of AR in weeks of poor disease control was 60.7% (P25-P75=24.9-74.2%), while partial and good disease control were respectively associated with an impact of 25.0% (P25-P75=12.1-42.4%) and 4.4% (P25-75=0.8-12.9%). In poorly-controlled weeks, presenteeism was associated with indirect costs ranging from 65.7 US Dollars purchase power parity (US$ PPPs) (P25-P75=29.2-143.2) in Brazil to 693.6 US$ PPP (P25-P75=405.2-1094.9) in Iceland. Median absenteeism per week was of 0% for all levels of rhinitis control. Patients with AR+asthma showed higher overall work impairment than patients with AR alone, particularly in poorly-controlled weeks (median work impairment in AR alone=39.1% [P25-P75=12.5-71.9%]; median work impairment in AR+asthma=68.4% [P25-P75=54.6-80.2%]). Conclusion Poor AR control was associated with decreased work productivity and increased indirect costs, particularly in patients with AR+asthma. The estimates from this study underpin the economic burden of AR.
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