Efficacy and Usability of a Cannabidiol-Infused Tampon for the Relief of Primary Dysmenorrhea

This study aimed to assess efficacy and usability of Cannabidiol (CBD) infused tampons for the relief of primary dysmenorrhea, a condition affecting 50-95% assigned female at birth. While primary dysmenorrhea affects a significant percentage of females, there remains a notable absence of specialized medications or devices to alleviate the intense pain that hinders daily activities. We have developed a CBD-infused tampon, lubricated for comfort and ease, recognising the potential benefits of cannabinoids in pain management. A randomized, single-blinded, placebo-controlled, non-interventional study was conducted with 63 participants, screened against an inclusion and exclusion criteria, following a review of their medical history, gynecological examination, and confirmation of the absence of pregnancy and sexually transmitted infections (STIs). Out of 114 screened individuals, 83 were eligible. Participants self-reported their pain levels and satisfaction with the CBD tampon using a modified Mankoski scale (1-10) for pain assessment. 63 participants completed the study, following through three consecutive menstruations. The CBD-infused tampon achieved statistically significant pain reduction during the first and third months of the study (p < 0.05). Less than 5% of participants experienced CBD-infused tampon-related irritation. Between 37-40% of the participants reported improvement in the level of vaginal dryness. This study supports the efficacy and usability of the CBD-infused tampon. The findings indicate the potential of CBD-infused tampons as a promising option for managing menstrual pain. Further research and exploration of this innovative product can contribute to the management of primary dysmenorrhea.