医学
外科
脊髓压迫
背景(考古学)
棕色肿瘤
椎管狭窄
减压
髂嵴
脊柱融合术
脊髓
椎管
放射科
甲状旁腺功能亢进
椎骨
继发性甲状旁腺功能亢进
甲状旁腺激素
古生物学
精神科
内科学
生物
钙
作者
Ramazan Kaya,Halit Çavuşoğlu,Canan Tanık,Okan Kahyaoğlu,Suna Dilbaz,Cengiz Tuncer,Yunus Aydın
标识
DOI:10.1016/j.spinee.2006.07.013
摘要
Background context Brown tumors are classic benign skeletal manifestations of hyperparathyroidism, but the spine involvement is very rare. Spinal reconstruction in these patients is controversial because of the severe osteoporosis and impaired bone healing. Of the reported 12 cases of spinal brown tumors in the literature, only in 5 were reconstructions with bone graft used. Purpose To describe our management in a patient with brown tumor and also to review the previous published cases. Study design Case report. Methods A case of a brown tumor in the T1 vertebra of a 72-year-old male patient is described. He had a previous diagnosis of secondary hyperthyroidism caused by renal failure. First, posterior transpedicular open biopsy was performed for the diagnosis and also for the decompression of the root causing brachialgia. After the diagnosis of a brown tumor, the patient was reoperated through anterior approach for total tumor removal and reconstruction of the spine. An autolog 3-cortical iliac crest strut graft was used for fusion, and medical treatment of hyperparathyroidism was given immediately after the operation. Decompression of spinal canal and fusion of bone graft was shown by a computed tomography scan 1 year after the operation. Results Complete resolution of the complaints of the patient and fusion of the graft were achieved. Conclusion The determination of a spinal tumor in a patient with renal failure and hyperparathyroidism should bring to mind the probability of a brown tumor. Although it is of a benign nature, it can cause severe neurologic deficit because of spinal compression. The recommended treatment modality is surgical resection of the tumor, spinal reconstruction, and aggressive treatment of hyperparathyroidism both with parathyroidectomy and medically.
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