Results of Trabeculectomy With Adjunctive Intraoperative Mitomycin C in Chinese Patients With Glaucoma

* BACKGROUND AND OBJECTIVE: To report the results of trabeculectomy with adjunctive intraoperative mitomycin C in Chinese patients with glaucoma. * PATIENTS AND METHODS: The medical records of Chinese patients who received trabeculectomy with intraoperative mitomycin C from 1992 to 1998 were retrospectively reviewed. A "successful" trabeculectomy was defined as one after which the intraocular pressure (IOP) could be controlled to between 5 and 21 mm Hg, inclusive, with no more than 3 glaucoma medications. * RESULTS: One hundred fourteen trabeculectomies in 105 eyes of 90 patients were retrospectively reviewed. Mean age ± standard deviation was 48.1 ± 21.9 years. Primary open-angle glaucoma (43.0%) and angle-closure glaucoma (27.2%) were the most common diagnoses leading to trabeculectomy. The mean follow-up ± standard deviation was 29.6 ± 18.6 months (range, 6 to 92 months). The overall success rate at the last followup was 73.7% (84 of 114 trabeculectomies). * CONCLUSIONS: Trabeculectomy with mitomycin C is a safe and effective procedure for the control of IOP in Chinese patients with glaucoma. [Ophthalmic Surg Lasers Imaging 2006;37:33-41.]