生物制造
3D生物打印
组织工程
计算机科学
纳米技术
生化工程
材料科学
生物医学工程
工程类
生物
生物技术
作者
Wei He,Jinjun Deng,Binghe Ma,Kai Tao,Zhi Zhang,Seeram Ramakrishna,Weizheng Yuan,Tao Ye
出处
期刊:ACS applied bio materials
[American Chemical Society]
日期:2023-12-13
标识
DOI:10.1021/acsabm.3c00806
摘要
3D bioprinting is recognized as a promising biomanufacturing technology that enables the reproducible and high-throughput production of tissues and organs through the deposition of different bioinks. Especially, bioinks based on loaded cells allow for immediate cellularity upon printing, providing opportunities for enhanced cell differentiation for organ manufacturing and regeneration. Thus, extensive applications have been found in the field of tissue engineering. The performance of the bioinks determines the functionality of the entire printed construct throughout the bioprinting process. It is generally expected that bioinks should support the encapsulated cells to achieve their respective cellular functions and withstand normal physiological pressure exerted on the printed constructs. The bioinks should also exhibit a suitable printability for precise deposition of the constructs. These characteristics are essential for the functional development of tissues and organs in bioprinting and are often achieved through the combination of different biomaterials. In this review, we have discussed the cutting-edge outstanding performance of different bioinks for printing various human tissues and organs in recent years. We have also examined the current status of 3D bioprinting and discussed its future prospects in relieving or curing human health problems.
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