疾病
医学
认知障碍
认知
认知功能衰退
阿尔茨海默病
生物标志物
长寿
痴呆
神经科学
老年学
精神科
心理学
病理
生物
生物化学
作者
Eric M. Reiman,Jeffrey L. Cummings,Jessica B. Langbaum,Soeren Mattke,Robert Alexander
标识
DOI:10.1016/s1474-4422(23)00508-2
摘要
Alzheimer's disease is the most common form of cognitive impairment. With increasing longevity, its prevalence continues to grow, and treatments that prevent its clinical onset would have a profound effect. Characterised by amyloid plaques, tau tangles, and neuronal loss, Alzheimer's pathology is already extensive and hard to stop by the time cognitive impairment is detected. Secondary prevention therapies have the potential to avert further disease progression and to stop or delay cognitive impairment in people with biomarker evidence of the disease.
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