Illuminating Cisplatin-induced Ferroptosis in Non-Small-Cell Lung Cancer with Biothiols-Activable Fluorescent/ Photoacoustic Bimodal Probes

Using activatable NIR fluorescent/PA bimodal probes, we successfully monitored real-time biothiol changes during ferroptosis in NSCLC cells and tumors, revealing enhanced ferroptosis with the combined use of erastin and cisplatin.