微体系结构
皮质骨
计算机科学
生物医学工程
解剖
医学
嵌入式系统
作者
Xiuyan Yang,Xicheng Chen,Chunhui Ji,Liang Zhang,Chuanbin Yan,Bin Lin,Juan Du,Zhen Wang
出处
期刊:Acta of Bioengineering and Biomechanics
[Politechnika Wroclawska Oficyna Wydawnicza]
日期:2024-01-01
卷期号:26 (2)
标识
DOI:10.37190/abb-02415-2024-03
摘要
Purpose This study aims to explore how the microarchitectural features of lacunae and perilacunar zones impact the biomechanics of microdamage accumulation in cortical bone, crucial for understanding bone disorders' pathogenesis and developing preventive measures. Methods Utilizing the phase-field finite element method, the study analyzed three bone unit models with varying microarchitecture: one without lacunae, one with lacunae, and one including perilacunar zones, to assess their effects on cortical bone's biomechanical properties. Results The presence of lacunae was found to increase microcrack initiation risk, acting as nucleation points and accelerating microcrack propagation. Proximity to Haversian canals exacerbated stress concentration, speeding microdamage progression. Conversely, perilacunar zones mitigated both initiation and propagation. An elevated critical energy release rate correlated with slower crack growth and reduced damage severity. Conclusions The research sheds light on the intricate mechanisms governing microcrack behavior in compact bone, highlighting the significant role of bone's microarchitectural features in its biomechanical response to microdamage. These insights are valuable for the development of strategies to prevent and treat bone-related disorders.
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