Self‐Produced O2 CNs‐Based Nanocarriers of DNA Hydrophobization Strategy Triggers Photodynamic and Mitochondrial‐Derived Ferroptosis for Hepatocellular Carcinoma Combined Treatment

Hypoxia can aggravate tumor occurrence, development, invasion, and metastasis, and greatly inhibit the photodynamic therapy (PDT) effect. Herein, carbon nitride (CNs)-based DNA and photosensitizer co-delivery systems (BPSCNs) with oxygen-producing functions are developed to address this problem. Selenide glucose (Seglu) is used as the dopant to prepare red/NIR-active CNs (SegluCNs). The tumor-targeting unit Bio-PEG