Coke oven gas contains fine particles and naphthalene, these impurities are easily deposited in equipment and pipelines and cause blockage. Moreover, it is extremely harmful to the human health and environment. In this paper, a pilot-scale experimental system was built employing a cross-flow rotating packed bed to explore the purification ability of the high gravity wet separation technology for naphthalene and the mixture of fine particles and naphthalene. It was shown that under the operating conditions of inlet gas naphthalene content of 5 mg/m3, high gravity factor of 83.70, gas velocity of 1.43 m/s and liquid spray density of 7.19 m3/(m2·h), the high gravity wet purification efficiency of naphthalene was 89.53%. At the inlet dust concentration of 50 mg/m3, the naphthalene content of 5 mg/m3, the gas velocity of 1.43 m/s, the high gravity factor of 83.70 and the liquid spray density of 6.0 m3/(m2·h), the purification efficiency of fine particles was as high as 99.23%, and the purification efficiency of naphthalene was 82.87%. It can be seen that high gravity wet purification technology possess a great potential for industrial application with better removal of naphthalene-containing gas as well as gas containing fine particles and naphthalene.