转录组
胰腺导管腺癌
组织重塑
胰腺癌
化生
癌症研究
转分化
癌症
腺泡细胞
腺癌
胰腺
医学
细胞生物学
病理
生物
基因
内科学
内分泌学
基因表达
炎症
干细胞
遗传学
作者
Jonathan Baldan,Juan Camacho-Roda,Marta Ballester,Kristina Høj,Anita Kurilla,H. Carlo Maurer,Sebastian Arcila-Barrera,Xinyi Lin,Zhaolong Pan,Joana Leitão-Castro,Alejandro Enrique Mayorca-Guiliani,Charlotte Vestrup Rift,Jane Preuss Hasselby,Luc Bouwens,Véronique Lefebvre,Charles J. David,Oren Parnas,Kathleen E. DelGiorno,Janine T. Erler,Ilse Rooman
出处
期刊:Gastroenterology
[Elsevier BV]
日期:2024-05-09
卷期号:167 (4): 718-732.e18
被引量:1
标识
DOI:10.1053/j.gastro.2024.04.031
摘要
Acinar-to-ductal metaplasia (ADM) is crucial in the development of pancreatic ductal adenocarcinoma. However, our understanding of the induction and resolution of ADM remains limited. We conducted comparative transcriptome analyses to identify conserved mechanisms of ADM in mouse and human.
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