乙酰转移酶
组蛋白乙酰转移酶
超家族
乙酰转移酶
生物化学
乙酰化
组蛋白乙酰转移酶
生物
化学
基因
作者
M.W. Vetting,Luiz Pedro S. de Carvalho,Michael C. Yu,Subray S. Hegde,Sophie Magnet,Steven L. Roderick,John S. Blanchard
标识
DOI:10.1016/j.abb.2004.09.003
摘要
The Gcn5-related N-acetyltransferases are an enormous superfamily of enzymes that are universally distributed in nature and that use acyl-CoAs to acylate their cognate substrates. In this review, we will examine those members of this superfamily that have been both structurally and mechanistically characterized. These include aminoglycoside N-acetyltransferases, serotonin N-acetyltransferase, glucosamine-6-phosphate N-acetyltransferase, the histone acetyltransferases, mycothiol synthase, protein N-myristoyltransferase, and the Fem family of amino acyl transferases.
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