Dr Blackstone is a unique scientific researcher and one of the most prolific and important cardiothoracic scientists of our time. Through his understanding of cardiothoracic surgery, computer programming, and statistical analysis, he has advanced cardiothoracic surgery research to a level that would not have been attainable without a person of his knowledge, skill, and dedication. His lifelong work has had a profound effect not only on our understanding of cardiothoracic surgical treatment but also on improving the care of patients with cardiothoracic disease.