荟萃分析
元回归
超重
切梅林
医学
肥胖
内科学
临床试验
回归分析
物理疗法
统计
数学
脂肪因子
胰岛素抵抗
作者
Damoon Ashtary‐Larky,Nasrin Lamuchi-Deli,Sara Kashkooli,Delsa Mombaini,Meysam Alipour,Fatemeh Khodadadi,Reza Bagheri,Frédéric Dutheil,Alexei Wong
标识
DOI:10.1080/13813455.2021.1892148
摘要
Context Elevated serum concentrations of chemerin is a significant factor in the development of metabolic disorders in individuals with overweight and obesity.Objective This systematic review, meta-analysis, and meta-regression evaluated the effects of exercise training on serum concentrations of chemerin in individuals with overweight and/or obesity.Methods Studies published up to January 2021 were identified through four databases. Forty-three studies including 1271 participants were included and analysed using a random-effects model to calculate weighted mean differences with 95% confidence intervals.Results Results indicated that exercise training significantly decreased serum concentrations of chemerin in individuals with overweight and/or obesity. Subgroup analysis showed that all types of exercise (aerobic, resistance, and combined training) interventions but not high-intensity interval training decreased serum concentrations of chemerin. Subgroup analysis based on baseline body mass index (BMI), gender, and intervention duration showed significant declines in serum concentrations of chemerin. Meta-regression analysis indicated a linear relationship between changes in body fat percentage (BFP) with serum concentrations of chemerin.Conclusion Exercise training may decrease serum concentrations of chemerin in individuals with overweight and/or obesity. The chemerin-lowering effects of exercise might be related to declines in BFP. Further studies are needed to confirm these findings.
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