医学
淋巴瘤
颈淋巴结病
荟萃分析
放射科
活检
置信区间
回顾性队列研究
内科学
疾病
作者
Anton Warshavsky,Roni Rosen,Chava Perry,Nidal Muhanna,Omer J. Ungar,Narin N. Carmel Neiderman,Dan M. Fliss,Gilad Horowitz
出处
期刊:Head & neck
[Wiley]
日期:2020-08-04
卷期号:42 (10): 3051-3060
被引量:10
摘要
Abstract Background The diagnostic yield of core needle biopsies (CNB) in cervical lymphadenopathy for lymphoma diagnosis is controversial. The aim of this study was to calculate the accuracy of cervical CNB in diagnosing lymphoma. Methods We conducted a meta‐analysis of all studies on patients presenting with cervical lymphadenopathy and referred to CNB. Patients with a diagnosis other than lymphoma were excluded. All cases diagnosed with lymphoma sufficient to guide treatment based on CNB outcome were considered accurate (actionable) results. A separate meta‐analysis was performed for various lymphoma subtypes. Results Three prospective and 19 retrospective studies, comprising 1120 patients, met the inclusion criteria. The rate of actionable lymphoma diagnoses following CNB ranged from 30% to 96.3%, with a random‐effects model of 82.45% (95% confidence interval [CI] =0.76‐0.88) and a fixed‐effects model of 78.3% (95% CI =0.75‐0.80). Conclusion CNB for cervical lymphadenopathy in lymphoma cases is relatively accurate in guiding treatment.
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