Progress in Percutaneous Penetration Enhancers from Traditional Chinese Medicines

Percutaneous penetration enhancers can regulate the transdermal absorption of drugs.Generally speaking, it can be divided into two categories: chemical synthesis and natural sources.Natural percutaneous penetration enhancers have the advantages of safety and mildness.This review summarizes the mechanism and characteristics of three kinds of percutaneous penetration enhancers and their combined application in transdermal drug delivery systems.The three different types of percutaneous penetration enhancers are fatty acids, alkaloids and terpenes.It is expected to provide considerations for the application research of percutaneous penetration enhancers rich in traditional Chinese medicines in transdermal drug delivery systems.