Advances in clinical treatment of MALT lymphoma

Mucosa-associated lymphoid tissue (MALT) lymphoma often occurs in the stomach as well as the head and neck. This disease has characteristics of multi-site dissemination and indolent development, and about 80% of MALT lymphoma patients are in early stage. Helicobacter pylori (Hp) eradication is the main method for treating early-stage Hp-positive gastric MALT lymphoma. For patients with other types of early-stage MALT lymphoma and those with gastric MALT lymphoma who failed Hp eradication therapy, radiotherapy has a good clinical effect. In recent years, radiotherapy target volume has changed from the involved field to the involved site, and the dose has been decreased. This article provides a review of the above aspects. Key words: Lymphoma, mucosa-associated lymphoid tissue; Helicobacter pylori; Radiotherapy