阿卡波糖
化学
糖苷
人参
槲皮素
五加科
传统医学
类黄酮
生物化学
立体化学
山奈酚
酶
抗氧化剂
医学
病理
替代医学
作者
Keke Li,Shasha Li,Fei Xu,Guiyun Cao,Xiao‐Jie Gong
标识
DOI:10.1080/14786419.2018.1543685
摘要
A novel acylated quercetin glycoside, floralpanasenoside A (1) and five known flavonoid glycosides, panasenoside (2), quercetin 3-O-(2''-β-D-glucopyranosyl)-β-D- galactopyranoside (3), trifolin (4) kaempferol 7-O-α-L-rhamnoside (5), and afzelin (6) were isolated from the flower buds of Panax ginseng. Their structures were established by spectroscopic data and comparison with the literature values. Four of the six isolated compounds including 1 (IC50 = 62.4) exhibited α-glucosidase inhibitory activity with IC50 values lower than acarbose (385.2 μM). The molecular docking study indicated that 1 bound to the active site of α-glucosidase with numerous hydrogen bond interactions.
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