生物
网状内皮组织增生病毒
基因
细胞质
分子生物学
胚胎
HSP2
视网膜母细胞瘤样蛋白1
细胞生物学
遗传学
肽序列
作者
Stephanie L. Simek,Rice Nr
出处
期刊:PubMed
日期:1988-01-01
卷期号:2 (2): 103-19
被引量:36
摘要
We have identified the protein encoded by chicken c-rel, the cellular homolog of the v-rel oncogene carried by reticuloendotheliosis virus. The protein has been detected in two avian lymphoid cell lines and in chick embryo fibroblasts. It has a molecular weight of 68,000, suggesting that the viral gene (which encodes a protein of 59,000 molecular weight) is a truncated form of its cellular homolog. The c-rel protein is found in the soluble cytoplasmic fraction of chicken lymphoid cells and is not associated in any stable way with other cellular proteins. Unlike the viral protein, p68c-rel is not detectably phosphorylated.
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