医学
梅德林
伊米奎莫德
重症监护医学
疤痕
循证医学
临床实习
激光治疗
皮肤病科
外科
替代医学
病理
物理疗法
激光器
物理
光学
政治学
法学
作者
Michael H. Gold,Brian Berman,Matteo Tretti Clementoni,Gerd G. Gauglitz,Foad Nahai,Crystal Murcia
出处
期刊:PubMed
日期:2014-08-01
卷期号:40 (8): 817-24
被引量:68
标识
DOI:10.1111/dsu.0000000000000049
摘要
There is an ongoing need to standardize scar management by establishing safe and effective treatment options that can be applied in routine clinical practice.To review available data on methods for preventing and treating cutaneous scarring.Relevant scientific literature was identified through a comprehensive search of the MEDLINE database. Additional data and published studies were submitted for consideration by members of the International Advisory Panel on Scar Management.One of the most significant advances in scar management over the past 10 years has been the broader application of laser therapy, resulting in a shift in status from an emerging technology to the forefront of treatment. Accumulated clinical evidence also supports a greater role for 5-fluourouracil in the treatment of hypertrophic scars and keloids, particularly in combination with intralesional corticosteroids. Encouraging data have been reported for newer therapies, including bleomycin, onion extract-containing preparations, imiquimod, and mitomycin C, although methodologic limitations in available studies merit consideration. In general, clinical and aesthetic outcomes seem to be enhanced by a combination approach to treatment.Advances in therapeutic options and new study data necessitate a revision of algorithms for the prevention and management of cutaneous scarring.
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