Exploring Th17‐related inflammation in AP1B1‐associated KIDAR syndrome and potential therapeutic implications of secukinumab

塞库金单抗 炎症 免疫学 化学 医学 关节炎 银屑病性关节炎
作者
Chaolan Pan,Hong‐Song Ge,Luyao Zheng,Qiaoyu Cao,Cheng Zhang,Yumeng Wang,Anqi Zhao,Wei He,Guofang Li,Haifei Liu,Yijun Yang,Ruoqu Wei,H Wang,Yidong Tan,Bing Wang,Wenjie Cheng,Zhe Sun,Xiaoxiao Wang,Ming Li
出处
标识
DOI:10.1111/jdv.20033
摘要

Journal of the European Academy of Dermatology and VenereologyEarly View LETTER TO THE EDITOR Exploring Th17-related inflammation in AP1B1-associated KIDAR syndrome and potential therapeutic implications of secukinumab Chaolan Pan, Chaolan Pan Department of Dermatology, Children's Hospital of Fudan University, National Children's Medical Center, Shanghai, China Department of Dermatology, Xinhua Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, ChinaSearch for more papers by this authorHongsong Ge, Hongsong Ge Department of Dermatology, Anhui Provincial Children's Hospital, Hefei, ChinaSearch for more papers by this authorLuyao Zheng, Luyao Zheng Department of Dermatology, Xinhua Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, ChinaSearch for more papers by this authorQiaoyu Cao, Qiaoyu Cao Department of Dermatology, Children's Hospital of Fudan University, National Children's Medical Center, Shanghai, ChinaSearch for more papers by this authorCheng Zhang, Cheng Zhang orcid.org/0000-0002-7735-7839 Department of Dermatology, Anhui Provincial Children's Hospital, Hefei, ChinaSearch for more papers by this authorYumeng Wang, Yumeng Wang orcid.org/0000-0002-5298-3171 Department of Dermatology, Children's Hospital of Fudan University, National Children's Medical Center, Shanghai, China Department of Dermatology, Xinhua Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China Institute of Dermatology, Shanghai Jiaotong University School of Medicine, Shanghai, ChinaSearch for more papers by this authorAnqi Zhao, Anqi Zhao Department of Dermatology, Children's Hospital of Fudan University, National Children's Medical Center, Shanghai, China Department of Dermatology, Xinhua Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China Institute of Dermatology, Shanghai Jiaotong University School of Medicine, Shanghai, ChinaSearch for more papers by this authorWei He, Wei He Department of Dermatology, Children's Hospital of Fudan University, National Children's Medical Center, Shanghai, ChinaSearch for more papers by this authorGuofang Li, Guofang Li Department of Dermatology, Xinhua Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China Institute of Dermatology, Shanghai Jiaotong University School of Medicine, Shanghai, ChinaSearch for more papers by this authorHaifei Liu, Haifei Liu orcid.org/0000-0002-6954-5899 Department of Dermatology, Xinhua Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China Institute of Dermatology, Shanghai Jiaotong University School of Medicine, Shanghai, ChinaSearch for more papers by this authorYijun Yang, Yijun Yang orcid.org/0000-0003-4974-8012 Department of Dermatology, Xinhua Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China Institute of Dermatology, Shanghai Jiaotong University School of Medicine, Shanghai, ChinaSearch for more papers by this authorRuoqu Wei, Ruoqu Wei orcid.org/0000-0001-8818-4534 Department of Dermatology, Xinhua Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China Institute of Dermatology, Shanghai Jiaotong University School of Medicine, Shanghai, ChinaSearch for more papers by this authorHaoyu Wang, Haoyu Wang orcid.org/0000-0003-3075-7840 Department of Dermatology, Xinhua Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China Institute of Dermatology, Shanghai Jiaotong University School of Medicine, Shanghai, ChinaSearch for more papers by this authorYidong Tan, Yidong Tan Department of Dermatology, Xinhua Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China Institute of Dermatology, Shanghai Jiaotong University School of Medicine, Shanghai, ChinaSearch for more papers by this authorBing Wang, Bing Wang Department of Dermatology, Xinhua Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China Institute of Dermatology, Shanghai Jiaotong University School of Medicine, Shanghai, ChinaSearch for more papers by this authorWenjie Cheng, Wenjie Cheng Department of Dermatology, Xinhua Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China Institute of Dermatology, Shanghai Jiaotong University School of Medicine, Shanghai, ChinaSearch for more papers by this authorZhe Sun, Zhe Sun Department of Dermatology, Xinhua Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China Institute of Dermatology, Shanghai Jiaotong University School of Medicine, Shanghai, ChinaSearch for more papers by this authorXiaoxiao Wang, Corresponding Author Xiaoxiao Wang [email protected] Department of Dermatology, Xinhua Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China Correspondence Ming Li, Department of Dermatology, Children's Hospital of Fudan University, National Children's Medical Center, 399 Wanyuan Road, Shanghai, China. Email: [email protected] Xiaoxiao Wang, Department of Dermatology, Xinhua Hospital, Shanghai Jiaotong University School of Medicine, Shanghai 200092, China. Email: [email protected]Search for more papers by this authorMing Li, Corresponding Author Ming Li [email protected] orcid.org/0000-0003-3053-2756 Department of Dermatology, Children's Hospital of Fudan University, National Children's Medical Center, Shanghai, China Correspondence Ming Li, Department of Dermatology, Children's Hospital of Fudan University, National Children's Medical Center, 399 Wanyuan Road, Shanghai, China. Email: [email protected] Xiaoxiao Wang, Department of Dermatology, Xinhua Hospital, Shanghai Jiaotong University School of Medicine, Shanghai 200092, China. Email: [email protected]Search for more papers by this author Chaolan Pan, Chaolan Pan Department of Dermatology, Children's Hospital of Fudan University, National Children's Medical Center, Shanghai, China Department of Dermatology, Xinhua Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, ChinaSearch for more papers by this authorHongsong Ge, Hongsong Ge Department of Dermatology, Anhui Provincial Children's Hospital, Hefei, ChinaSearch for more papers by this authorLuyao Zheng, Luyao Zheng Department of Dermatology, Xinhua Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, ChinaSearch for more papers by this authorQiaoyu Cao, Qiaoyu Cao Department of Dermatology, Children's Hospital of Fudan University, National Children's Medical Center, Shanghai, ChinaSearch for more papers by this authorCheng Zhang, Cheng Zhang orcid.org/0000-0002-7735-7839 Department of Dermatology, Anhui Provincial Children's Hospital, Hefei, ChinaSearch for more papers by this authorYumeng Wang, Yumeng Wang orcid.org/0000-0002-5298-3171 Department of Dermatology, Children's Hospital of Fudan University, National Children's Medical Center, Shanghai, China Department of Dermatology, Xinhua Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China Institute of Dermatology, Shanghai Jiaotong University School of Medicine, Shanghai, ChinaSearch for more papers by this authorAnqi Zhao, Anqi Zhao Department of Dermatology, Children's Hospital of Fudan University, National Children's Medical Center, Shanghai, China Department of Dermatology, Xinhua Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China Institute of Dermatology, Shanghai Jiaotong University School of Medicine, Shanghai, ChinaSearch for more papers by this authorWei He, Wei He Department of Dermatology, Children's Hospital of Fudan University, National Children's Medical Center, Shanghai, ChinaSearch for more papers by this authorGuofang Li, Guofang Li Department of Dermatology, Xinhua Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China Institute of Dermatology, Shanghai Jiaotong University School of Medicine, Shanghai, ChinaSearch for more papers by this authorHaifei Liu, Haifei Liu orcid.org/0000-0002-6954-5899 Department of Dermatology, Xinhua Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China Institute of Dermatology, Shanghai Jiaotong University School of Medicine, Shanghai, ChinaSearch for more papers by this authorYijun Yang, Yijun Yang orcid.org/0000-0003-4974-8012 Department of Dermatology, Xinhua Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China Institute of Dermatology, Shanghai Jiaotong University School of Medicine, Shanghai, ChinaSearch for more papers by this authorRuoqu Wei, Ruoqu Wei orcid.org/0000-0001-8818-4534 Department of Dermatology, Xinhua Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China Institute of Dermatology, Shanghai Jiaotong University School of Medicine, Shanghai, ChinaSearch for more papers by this authorHaoyu Wang, Haoyu Wang orcid.org/0000-0003-3075-7840 Department of Dermatology, Xinhua Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China Institute of Dermatology, Shanghai Jiaotong University School of Medicine, Shanghai, ChinaSearch for more papers by this authorYidong Tan, Yidong Tan Department of Dermatology, Xinhua Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China Institute of Dermatology, Shanghai Jiaotong University School of Medicine, Shanghai, ChinaSearch for more papers by this authorBing Wang, Bing Wang Department of Dermatology, Xinhua Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China Institute of Dermatology, Shanghai Jiaotong University School of Medicine, Shanghai, ChinaSearch for more papers by this authorWenjie Cheng, Wenjie Cheng Department of Dermatology, Xinhua Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China Institute of Dermatology, Shanghai Jiaotong University School of Medicine, Shanghai, ChinaSearch for more papers by this authorZhe Sun, Zhe Sun Department of Dermatology, Xinhua Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China Institute of Dermatology, Shanghai Jiaotong University School of Medicine, Shanghai, ChinaSearch for more papers by this authorXiaoxiao Wang, Corresponding Author Xiaoxiao Wang [email protected] Department of Dermatology, Xinhua Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China Correspondence Ming Li, Department of Dermatology, Children's Hospital of Fudan University, National Children's Medical Center, 399 Wanyuan Road, Shanghai, China. Email: [email protected] Xiaoxiao Wang, Department of Dermatology, Xinhua Hospital, Shanghai Jiaotong University School of Medicine, Shanghai 200092, China. Email: [email protected]Search for more papers by this authorMing Li, Corresponding Author Ming Li [email protected] orcid.org/0000-0003-3053-2756 Department of Dermatology, Children's Hospital of Fudan University, National Children's Medical Center, Shanghai, China Correspondence Ming Li, Department of Dermatology, Children's Hospital of Fudan University, National Children's Medical Center, 399 Wanyuan Road, Shanghai, China. Email: [email protected] Xiaoxiao Wang, Department of Dermatology, Xinhua Hospital, Shanghai Jiaotong University School of Medicine, Shanghai 200092, China. Email: [email protected]Search for more papers by this author First published: 20 April 2024 https://doi.org/10.1111/jdv.20033 Chaolan Pan and Hongsong Ge contribute equally to this paper. Read the full textAboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onEmailFacebookTwitterLinkedInRedditWechat Open Research DATA AVAILABILITY STATEMENT The data that support the findings of this study are available from the corresponding author upon reasonable request. REFERENCES 1Gan Y, McGraw TE, Rodriguez-Boulan E. The epithelial-specific adaptor AP1B mediates post-endocytic recycling to the basolateral membrane. Nat Cell Biol. 2002; 4(8): 605–609. 10.1038/ncb827 CASPubMedWeb of Science®Google Scholar 2Fölsch H. Role of the epithelial cell-specific clathrin adaptor complex AP-1B in cell polarity. Cell Logist. 2015; 5(2):e1074331. 10.1080/21592799.2015.1074331 PubMedGoogle Scholar 3Boyden LM, Atzmony L, Hamilton C, Zhou J, Lim YH, Hu R, et al. Recessive mutations in AP1B1 cause ichthyosis, deafness, and photophobia. Am J Hum Genet. 2019; 105(5): 1023–1029. 10.1016/j.ajhg.2019.09.021 CASPubMedWeb of Science®Google Scholar 4Alsaif HS, Al-Owain M, Barrios-Llerena ME, Gosadi G, Binamer Y, Devadason D, et al. Homozygous loss-of-function mutations in AP1B1, encoding Beta-1 subunit of adaptor-related protein complex 1, cause MEDNIK-like syndrome. Am J Hum Genet. 2019; 105(5): 1016–1022. 10.1016/j.ajhg.2019.09.020 CASPubMedWeb of Science®Google Scholar 5Lee MY, Wang HZ, White TW, Brooks T, Pittman A, Halai H, et al. Allele-specific small interfering RNA corrects aberrant cellular phenotype in keratitis-ichthyosis-deafness syndrome keratinocytes. J Invest Dermatol. 2020; 140(5): 1035–1044. 10.1016/j.jid.2019.09.022 CASPubMedWeb of Science®Google Scholar 6Patel V, Sun G, Dickman M, Khuu P, Teng JM. Treatment of keratitis-ichthyosis- deafness (KID) syndrome in children: a case report and review of the literature. Dermatol Ther. 2015; 28(2): 89–93. 10.1111/dth.12192 PubMedWeb of Science®Google Scholar 7Yoneda K. Inherited ichthyosis: syndromic forms. J Dermatol. 2016; 43(3): 252–263. 10.1111/1346-8138.13284 PubMedWeb of Science®Google Scholar Early ViewOnline Version of Record before inclusion in an issue ReferencesRelatedInformation

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