The metabolic processes of fruits induce water vapor condensation in packaging, creating a high-humidity microenvironment that exacerbates the proliferation of microorganisms and causes food spoilage. Therefore, a Fe/Zr bimetallic organic framework (Fe-MOF-801) packaging (i.e., FeMGCF) with high binding stability to transpiration water was prepared based on transition metal Fe doping strategy, and the mechanism of its enhanced binding stability towards transpiration water was investigated. The results indicate that Fe enhances the interaction between MOFs and H