纤维素
生物传感器
瓜尔胶
纳米纤维
基质(水族馆)
化学
阳离子聚合
色谱法
化学工程
材料科学
高分子化学
纳米技术
生物化学
生物
生态学
工程类
作者
Lei Dai,Yijiao Xue,Sihan Tian,Ping He,Pan Xie,Zhu Long,Guiqiang Fei,Zhi‐Rong Chen
标识
DOI:10.1016/j.ijbiomac.2024.133497
摘要
The monitoring of foodborne bacterial contamination requires simple and convenient biosensors. This work describes a novel paper-based colorimetric biosensor for the rapid and sensitive bacteria detection. The biosensor was constructed via the encapsulation of D-alanyl-D-alanine capped gold nanoparticles (DADA-AuNPs) in a modified paper that was fabricated by the freeze-drying of TEMPO-oxidized cellulose nanofibers/cationic guar gum composite hydrogel-modified filter paper. The results indicated that the size of DADA-AuNPs largely determined the color of their aqueous system and they exhibited light red to dark red as their size increased from around 6 to 36 nm. All these different sized DADA-AuNPs turned into colorless when encountered with either S. aureus or E. coli. In particular, the smaller the DADA-AuNPs size, the faster the discoloration. The encapsulation of DADA-AuNPs into modified paper negligibly changed their responsiveness towards bacteria. In comparison to the original filter paper and oven-dried hydrogel-modified filter paper, the freeze-dried hydrogel-modified paper was demonstrated to be a better substrate for the encapsulation of DADA-AuNPs since they could be loaded with a larger amount of DADA-AuNPs in a faster way and showed a better perceivable color. This work demonstrated a promising paper-based colorimetric biosensor for the facile and rapid detection of bacteria.
科研通智能强力驱动
Strongly Powered by AbleSci AI