Vaginal Drug Delivery: The First Uterine Pass Effecta

妇产科学 医学 妇科 图书馆学 怀孕 遗传学 计算机科学 生物
作者
Carlo Bulletti,Dominique de Ziegler,E. Giacomucci,V. Polli,Stefania Rossi,S Alfieri,C Flamigni
出处
期刊:Annals of the New York Academy of Sciences [Wiley]
卷期号:828 (1): 285-290 被引量:42
标识
DOI:10.1111/j.1749-6632.1997.tb48549.x
摘要

Annals of the New York Academy of SciencesVolume 828, Issue 1 p. 285-290 Vaginal Drug Delivery: The First Uterine Pass Effecta CARLO BULLETTI, Corresponding Author CARLO BULLETTI b1st Institute of Obstetrics and Gynecology University of Bologna—Italy Via Massarenti, 13 40138 Bologna, Italyd1st Institute of Obstetrics and Gynecology University of Bologna—Italy Via Massarenti, 13 40138 Bologna, ItalySearch for more papers by this authorDOMINIQUE DE ZIEGLER, DOMINIQUE DE ZIEGLER Columbia Laboratoires Paris, FranceSearch for more papers by this authorEVALDO GIACOMUCCI, EVALDO GIACOMUCCI b1st Institute of Obstetrics and Gynecology University of Bologna—Italy Via Massarenti, 13 40138 Bologna, ItalySearch for more papers by this authorVALERIA POLLI, VALERIA POLLI b1st Institute of Obstetrics and Gynecology University of Bologna—Italy Via Massarenti, 13 40138 Bologna, ItalySearch for more papers by this authorSTEFANIA ROSSI, STEFANIA ROSSI b1st Institute of Obstetrics and Gynecology University of Bologna—Italy Via Massarenti, 13 40138 Bologna, ItalySearch for more papers by this authorSTEFANIA ALFIERI, STEFANIA ALFIERI b1st Institute of Obstetrics and Gynecology University of Bologna—Italy Via Massarenti, 13 40138 Bologna, ItalySearch for more papers by this authorCARLO FLAMIGNI, CARLO FLAMIGNI b1st Institute of Obstetrics and Gynecology University of Bologna—Italy Via Massarenti, 13 40138 Bologna, ItalySearch for more papers by this author CARLO BULLETTI, Corresponding Author CARLO BULLETTI b1st Institute of Obstetrics and Gynecology University of Bologna—Italy Via Massarenti, 13 40138 Bologna, Italyd1st Institute of Obstetrics and Gynecology University of Bologna—Italy Via Massarenti, 13 40138 Bologna, ItalySearch for more papers by this authorDOMINIQUE DE ZIEGLER, DOMINIQUE DE ZIEGLER Columbia Laboratoires Paris, FranceSearch for more papers by this authorEVALDO GIACOMUCCI, EVALDO GIACOMUCCI b1st Institute of Obstetrics and Gynecology University of Bologna—Italy Via Massarenti, 13 40138 Bologna, ItalySearch for more papers by this authorVALERIA POLLI, VALERIA POLLI b1st Institute of Obstetrics and Gynecology University of Bologna—Italy Via Massarenti, 13 40138 Bologna, ItalySearch for more papers by this authorSTEFANIA ROSSI, STEFANIA ROSSI b1st Institute of Obstetrics and Gynecology University of Bologna—Italy Via Massarenti, 13 40138 Bologna, ItalySearch for more papers by this authorSTEFANIA ALFIERI, STEFANIA ALFIERI b1st Institute of Obstetrics and Gynecology University of Bologna—Italy Via Massarenti, 13 40138 Bologna, ItalySearch for more papers by this authorCARLO FLAMIGNI, CARLO FLAMIGNI b1st Institute of Obstetrics and Gynecology University of Bologna—Italy Via Massarenti, 13 40138 Bologna, ItalySearch for more papers by this author First published: 17 December 2006 https://doi.org/10.1111/j.1749-6632.1997.tb48549.xCitations: 29 a This work was supported by grants from Columbia Laboratoires (Paris, France) and the National Research Council (No. 9500829). Read the full textAboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onEmailFacebookTwitterLinkedInRedditWechat REFERENCES 1 Mizutani, T., S. Nishiyama, I. Amakawa, A. Watanabe, K. Nakamuro & N. Terada. 1995. Danazol concentrations in ovary, uterus, and serum and their effect on the hypothalamic-pituitary-ovarian axis during vaginal administration of danazol suppository. Fertil. Steril. 63: 1184–1189. 2 Kullander, S. & Svanberg. 1985. On resorption and the effects of vaginally administered terbutaline in women with premature labor. Acta Obstet. Gynecol. Scand. 64: 613–616. 3 Bulletti, C., V. M. Jasonni, S. Lubicz, C. Flamigni & E. Gurpide. 1986. Extracorporeal perfusion of the human uterus. Am. J. Obstet. Gynecol. 154: 683–688. 4 Bulletti, C., V. M. Jasonni, P. M. Ciotti, S. Tabanelli, S. Naldi & C. Flamigni. 1988. Extraction of estrogens by human perfused uterus. Effects of membrane permeability and binding by serum proteins on differential influx into the endometrium and myometrium. Am. J. Obstet. Gynecol. 159: 509–515. 5 Bulletti, C., V. M. Jasonni, G. Martinelli, E. Govoni, S. Tabanelli, P. M. Ciotti & C. Flamigni. 1987. A 48-hour preservation of an isolated human uterus: Endometrial responses to sex steroids. Fertil. Steril. 47(1): 122–129. 6 Bulletti, C., V. M. Jasonni, S. Tabanelli, L. Gianaroli, P. M. Ciotti, A. P. Ferraretti & C. Flamigni. 1988. Early human pregnancy in vitro utilizing an artificially perfused uterus. Fertil. Steril. 49: 991–996. 7 Pardridge, W. M. 1981. Transport of protein-bound hormones into tissues in vivo. Endocr. Rev. 2: 103–123. 8 Pardridge, W. M. & L. J. Mietus. 1979. Transport of steroid hormones through the rat blood-brain barrier: Primary role of albumin-bound hormone. J. Clin. Invest. 64: 145–154. 9 Miles, R. A., R. J. Paulson, R. A. Lobo, M. F. Press, L. Dahmoush & M. V. Sauer. 1994. Pharmacokinetics and endometrial tissue levels of pogesterone after administration by intramuscular and vaginal routes: A comparative study. Fertil. Steril. 62: 485–490. 10 Bulletti, C., R. A. Prefetto, G. Bazzocchi, R. Romero, P. Mimmi, V. Polli, G. A. Lanfranchi, A. Morselli Labbate & C. Flamigni. 1993. Electromechanical activities of human uteri during the extracorporeal perfusion with ovarian steroids. Hum. Reprod. 8: 1558–1563. Citing Literature Volume828, Issue1Uterus, The: Endometrium and MyometriumSeptember 1997Pages 285-290 ReferencesRelatedInformation
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