化学
金属转移
硝化作用
芳基
催化作用
硝基
组合化学
相容性(地球化学)
有机化学
化学工程
烷基
工程类
作者
Brett P. Fors,Stephen L. Buchwald
摘要
An efficient Pd catalyst for the transformation of aryl chlorides, triflates, and nonaflates to nitroaromatics has been developed. This reaction proceeds under weakly basic conditions and displays a broad scope and excellent functional group compatibility. Moreover, this method allows for the synthesis of aromatic nitro compounds that cannot be accessed efficiently via other nitration protocols. Mechanistic insight into the transmetalation step of the catalytic process is also reported.
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