噬菌体
寄主(生物学)
受体
生物
化学
吸附
计算生物学
微生物学
生态学
遗传学
基因
大肠杆菌
有机化学
作者
Juliano Bertozzi Silva,Zachary J. Storms,Dominic Sauvageau
标识
DOI:10.1093/femsle/fnw002
摘要
The adsorption of bacteriophages (phages) onto host cells is, in all but a few rare cases, a sine qua non condition for the onset of the infection process. Understanding the mechanisms involved and the factors affecting it is, thus, crucial for the investigation of host-phage interactions. This review provides a survey of the phage host receptors involved in recognition and adsorption and their interactions during attachment. Comprehension of the whole infection process, starting with the adsorption step, can enable and accelerate our understanding of phage ecology and the development of phage-based technologies. To assist in this effort, we have established an open-access resource--the Phage Receptor Database (PhReD)--to serve as a repository for information on known and newly identified phage receptors.
科研通智能强力驱动
Strongly Powered by AbleSci AI