Changes in plasma phospholipids and sphingomyelins with aging in men and women: A comprehensive systematic review of longitudinal cohort studies

医学 鞘磷脂 内科学 老年学 斯科普斯 梅德林 队列 队列研究 胆固醇 内分泌学 生物 生物化学
作者
Niyaz Mohammadzadeh Honarvar,Meysam Zarezadeh,Samantha Molsberry,Alberto Ascherio
出处
期刊:Ageing Research Reviews [Elsevier]
卷期号:68: 101340-101340 被引量:9
标识
DOI:10.1016/j.arr.2021.101340
摘要

Aging affects the serum levels of various metabolites which may be involved in the pathogenesis of chronic diseases. The aim of this review article is to summarize the relationship between aging and alterations in the plasma phospholipids and sphingomyelins. PRISMA guidelines were employed during all steps. MEDLINE (PubMed), Scopus, Embase and Web of Sciences databases and Google Scholar were searched up to October 2020. Cohort studies investigating the relationship between aging and within-person changes in sphingomyelin (SM), phosphatidyl choline (PC), lyso PC (LPC) and phosphatidyl ethanolamine (PE) were included. Newcastle-Ottawa scale was used to assess the quality of included studies. A total of 1425 studies were identified. After removing 610 duplicates and 723 irrelevant studies, full texts of 92 articles were evaluated. Of these 92, 6 studies (including data from 7 independent cohorts) met the inclusion criteria and are included in this review. All study populations were healthy and included both men and women. Results by sex were reported in 3 cohorts for PC, 5 cohorts for LPC, 3 cohorts for SM, and only 1 cohort for PE. In men, PC, SM, PE and LPC decreased with aging, although results for LPC were inconsistent. In women, LPC, SM, and PE increased age, whereas changes in PC were inconsistent. Within-person serum levels of phospholipids and sphingomyelins, decrease during aging in men and increase in women. Notably, however, there were some inconsistencies across studies of LPC in men and of PC in women.
最长约 10秒,即可获得该文献文件

科研通智能强力驱动
Strongly Powered by AbleSci AI
更新
大幅提高文件上传限制,最高150M (2024-4-1)

科研通是完全免费的文献互助平台,具备全网最快的应助速度,最高的求助完成率。 对每一个文献求助,科研通都将尽心尽力,给求助人一个满意的交代。
实时播报
Starwalker完成签到,获得积分0
刚刚
刚刚
1秒前
SciGPT应助申思采纳,获得10
1秒前
2秒前
3秒前
4秒前
稳如老狗发布了新的文献求助10
5秒前
6秒前
fleee发布了新的文献求助10
7秒前
NexusExplorer应助炙热谷雪采纳,获得10
8秒前
9秒前
林机一动发布了新的文献求助10
9秒前
勤奋紫真发布了新的文献求助10
11秒前
拼搏向上发布了新的文献求助10
13秒前
13秒前
er发布了新的文献求助10
13秒前
独特觅翠完成签到 ,获得积分10
14秒前
科研通AI2S应助周涛采纳,获得10
17秒前
18秒前
kiki完成签到 ,获得积分10
18秒前
天天快乐应助Messi采纳,获得10
19秒前
23秒前
充电宝应助靓仔采纳,获得10
25秒前
勤奋紫真完成签到 ,获得积分20
28秒前
28秒前
汉堡包应助er采纳,获得10
29秒前
29秒前
31秒前
32秒前
搜集达人应助司宁采纳,获得10
33秒前
丘比特应助飘扬采纳,获得10
33秒前
11发布了新的文献求助10
34秒前
ningning完成签到 ,获得积分10
34秒前
zhaozhao发布了新的文献求助10
35秒前
bang269发布了新的文献求助30
36秒前
煎饼果子不加葱完成签到,获得积分10
36秒前
司宁完成签到,获得积分10
41秒前
小墨驳回了榴莲应助
43秒前
45秒前
高分求助中
Sustainability in Tides Chemistry 2800
The Young builders of New china : the visit of the delegation of the WFDY to the Chinese People's Republic 1000
Rechtsphilosophie 1000
Bayesian Models of Cognition:Reverse Engineering the Mind 888
Le dégorgement réflexe des Acridiens 800
Defense against predation 800
Very-high-order BVD Schemes Using β-variable THINC Method 568
热门求助领域 (近24小时)
化学 医学 生物 材料科学 工程类 有机化学 生物化学 物理 内科学 纳米技术 计算机科学 化学工程 复合材料 基因 遗传学 催化作用 物理化学 免疫学 量子力学 细胞生物学
热门帖子
关注 科研通微信公众号,转发送积分 3136141
求助须知:如何正确求助?哪些是违规求助? 2787040
关于积分的说明 7780388
捐赠科研通 2443192
什么是DOI,文献DOI怎么找? 1298921
科研通“疑难数据库(出版商)”最低求助积分说明 625294
版权声明 600870