Red Blood Cell Superstructures: Modular Assembly of Red Blood Cell Superstructures from Metal–Organic Framework Nanoparticle‐Based Building Blocks (Adv. Funct. Mater. 10/2021)

In article number 2005935, Wei Zhu, Stefan Wuttke, C. Jeffrey Brinker, and co-workers assemble native red blood cells (RBCs) within and protected by functional exoskeletons of interlinked MOF nanoparticles. The armored RBCs preserve the original properties of RBCs (oxygen storage) and inherit the exogenous properties of functionalizing nanoparticles. Their synthesis is generalizable and creates novel hybrid biomaterials for endogenous in vivo sensing and biorthogonal imaging applications.