萃取(化学)
喜树碱
产量(工程)
化学
粒径
色谱法
动能
占空比
粒子(生态学)
材料科学
分析化学(期刊)
热力学
有机化学
冶金
物理化学
物理
地质学
功率(物理)
海洋学
量子力学
作者
Dhiraj M. Patil,Krishnacharya G. Akamanchi
标识
DOI:10.1016/j.ultsonch.2017.02.015
摘要
Ultrasound-assisted extraction (UAE) of commercially important natural product camptothecin (CPT) from Nothapodytes nimmoniana plant has been investigated. The influences of process factors such as electric acoustic intensity, solid to liquid ratio, duty cycle, temperature and particle size on the maximum extraction yield and kinetic mechanisms of the entire extraction process have been investigated. The kinetics results showed that increasing the intensity, duty cycle, solid to liquid ratio and decreasing the particle size lead to substantial increase in extraction yields compared to classical stirring extraction. Different kinetic models were applied to fit the experimental data. The second order rate model appears to be the best. The extraction rate constant, initial extraction rate and the equilibrium concentration for all experimental conditions have been calculated. SEM analysis of spent plant material clearly showed hollow openings on cell structure, which could be directly correlated to explosive disruption by the action of ultrasound waves. Overall 1.7-fold increase in extraction yields of CPT (0.32% w/w) and decrease in time from 6h to 18min was observed over the stirring method.
科研通智能强力驱动
Strongly Powered by AbleSci AI