催化作用
水解
化学
双金属片
级联
组合化学
儿茶酚
金属有机骨架
协同催化
纳米技术
有机化学
材料科学
吸附
色谱法
作者
Sheng Liu,Yang He,Weikun Zhang,Tao Fu,Liangjie Wang,Yixin Zhang,Xu Yi,Hao Sun,Huazhang Zhao
出处
期刊:Small
[Wiley]
日期:2023-10-26
卷期号:20 (10)
被引量:9
标识
DOI:10.1002/smll.202306522
摘要
Abstract Mimicking efficient biocatalytic cascades using nanozymes has gained enormous attention in catalytic chemistry, but it remains challenging to develop a nanozyme‐based cascade system to sequentially perform the desired reactions. Particularly, the integration of sequential hydrolysis and oxidation reactions into nanozyme‐based cascade systems has not yet been achieved, despite their significant roles in various domains. Herein, a self‐cascade Ce‐MOF‐818 nanozyme for sequential hydrolysis and oxidation reactions is developed. Ce‐MOF‐818 is the first Ce(IV)‐based heterometallic metal–organic framework constructed through the coordination of Ce and Cu to distinct groups. It is successfully synthesized using an improved solvothermal method, overcoming the challenge posed by the significant difference in the binding speeds of Ce and Cu to ligands. With excellent organophosphate hydrolase‐like ( K m = 42.3 µ M , K cat = 0.0208 min −1 ) and catechol oxidase‐like ( K m = 2589 µ M , K cat = 1.25 s −1 ) activities attributed to its bimetallic active centers, Ce‐MOF‐818 serves as a promising self‐cascade platform for sequential hydrolysis and oxidation. Notably, its catalytic efficiency surpasses that of physically mixed nanozymes by approximately fourfold, owning to the close integration of active sites. The developed hydrolysis–oxidation self‐cascade nanozyme has promising potential applications in catalytic chemistry and provides valuable insights into the rational design of nanozyme‐based cascade systems.
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