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Blood pressure response during exercise testing in individuals with and without hypertension: The value of the recovery phase

医学 血压 舒张期 心脏病学 内科学 心率 体质指数 队列 原发性高血压 高血压前期
作者
Céline Ghidoni,Jan Gerrit van der Stouwe,Laura Würzburger,Patrick Wiech,Jan Vontobel,Philipp Bohm,Georg Moser,Gloria Petrasch,Valentina A. Rossi,Christian Schmied,Stefano Caselli,David Niederseer
出处
期刊:European Journal of Clinical Investigation [Wiley]
卷期号:54 (11)
标识
DOI:10.1111/eci.14285
摘要

Abstract Background Hypertension and exercise testing are essential for cardiovascular risk assessment. However, an exact description of blood pressure (BP) in patients with a hypertensive response during exercise (HRE), especially in the recovery phase is lacking. Herein, we aimed to analyse BP and heart rate during exercise testing and recovery in patients with an HRE. Methods 800 patients aged 17–90 with an HRE during a standardized bicycle ergometry test were recruited. The BP behaviour during exercise testing was correlated with clinical data. Furthermore, data were analysed according to the presence of pre‐existent hypertension. Results Of the 800 patients included in this study 497 (62%) were previously diagnosed with hypertension. Analysis of covariance showed a significantly faster systolic ( β [95% CI] 8.0 [4.9–11.1]) and diastolic (2.4 [0.4–4.4]) BP recovery 3 min after maximal exercise in patients without hypertension in univariable models. These results remained robust in fully adjusted models taking into account age, sex, body mass index, cardiovascular disease, and antihypertensive treatment for systolic (5.3 [1.2–9.4]) and diastolic BP (4.5 [1.9–7.0]). Furthermore, patients with hypertension displayed higher systolic BP during maximal exercise in univariable (3.8 [0.1–7.5]) and fully adjusted (5.5 [1.1–10.0]) models. There was no difference in maximum diastolic BP between groups. Conclusion In this large cohort study, patients without hypertension showed a faster systolic and diastolic BP recovery and lower maximal systolic BP compared to patients with hypertension. Overall, this study provides new insights into cardiovascular health during recovery phase.
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