化学
吲唑
芳基
功能群
组合化学
基质(水族馆)
产量(工程)
反应条件
分子
范围(计算机科学)
有机化学
催化作用
冶金
材料科学
程序设计语言
聚合物
烷基
地质学
海洋学
计算机科学
作者
Kai Sun,Bing Yu,Anzai Shi,Panjie Xiang,Yanxuan Wu,Chunhua Ge,Yan Liu
出处
期刊:Synlett
[Georg Thieme Verlag KG]
日期:2022-09-08
卷期号:34 (05): 457-464
被引量:3
摘要
Abstract An efficient approach for the photosynthesis of various arylated 2-aryl-2H-indazoles (38 examples) in moderate to good yields (up to 87% yield) under mild conditions was developed by employing 1,2,3,5-tetrakis(carbazol-9-yl)-4,6-dicyanobenzene (4CzIPN) as an inexpensive photocatalyst. This protocol features wide substrate scope, good functional group tolerance, and operational simplicity. In addition, the strategy was successfully applied to the late-stage modification of drug molecules, and the meaningful introduction of complex drugs to the skeleton of 2H-Indazole was achieved for the first time.
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