Alkoxy Radical Induced Transformations from N‐Alkoxyphthalimides Under the Photoredox Catalysis

Abstract Photocatalytic generation of alkoxy radicals is fast emerging as an essential method for the generation of diverse and valuable radicals from inert C−H and C−C bonds for the construction of various C(sp 3 )−C(sp 3 ), C(sp 3 )−C(sp 2 ), C(sp 3 )−C(sp), and C−heteroatom bonds under mild condition. This review is a comprehensive evaluation of the studies using N‐ alkoxyphthalimide (NAPI) derivatives as tunable oxygen radical precursors in photoredox catalysis, highlighting alkoxy radical enabled 1,2‐, 1,5‐hydrogen atom transfer, and β ‐fragmentation (deformylation) process to generate versatile carbon‐centered radical intermediates with diverse reactivity profiles.