材料科学
光热治疗
生物相容性
纳米复合材料
抗菌活性
光热效应
纳米技术
生物膜
纳米颗粒
胶体金
纳米材料
复合材料
化学工程
细菌
冶金
生物
遗传学
作者
Yujie Cai,Luyao Wang,Hong Hu,Wei Bing,Limei Tian,Jie Zhao
出处
期刊:Nanotechnology
[IOP Publishing]
日期:2020-12-01
卷期号:32 (8): 085102-085102
被引量:6
标识
DOI:10.1088/1361-6528/abc98e
摘要
Abstract Herein, we successfully developed a new multifunctional antibacterial system, which combined mechano-bactericidal (Au-nanostars) and photothermal (MoS 2 ) mechanism. Meanwhile, the targeting molecule of vancomycin was modified on the surface of MoS 2 –Au nanocomposites (Van-MoS 2 –Au), that generally yield high efficiency in antibacterial performance due to their effective working radii. Van-MoS 2 –Au nanocomposites were capable of completely destroying both gram-negative ( E. coli ) and gram-positive ( B. subtilis ) bacteria under 808 NIR laser irradiation for 20 min, and nearly no bacterial growth was detected after 12 h incubation. Moreover, these nanocomposites could destruct the refractory biofilm as well, which was a much more difficult medical challenge. The new antibacterial nanomaterials might offer many biomedical applications because of the biocompatibility and strong antibacterial ability.
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