哮喘
医学
疾病
重症监护医学
生物标志物
介绍(产科)
内型
免疫学
生物信息学
内科学
生物
生物化学
放射科
作者
Dharani Kumari Narendra,John Blixt,Nicola A. Hanania
标识
DOI:10.1016/j.smim.2019.101332
摘要
Severe asthma is heterogeneous in its clinical presentation, underlying pathophysiology, course and response to therapy. Clinical and physiological assessment of severe asthma is often inadequate in predicting underlying disease mechanisms and or response to medications. With the emergence of novel targeted therapies in severe asthma, the need for reproducible, easily measured biomarkers became obvious but only few are currently available for clinical use. These biomarkers along with the clinical presentation of the patient play an important role in identifying phenotypes and endotypes, predicting the clinical course and prognosis and improving the precision therapeutic approach to asthma.
科研通智能强力驱动
Strongly Powered by AbleSci AI