恶二唑
可扩展性
三苯基膦
组合化学
三苯基氧化膦
化学
过程(计算)
计算机科学
有机化学
催化作用
操作系统
作者
K. A. LUKIN,Vimal Kishore,Thomas D. Gordon
摘要
A robust and scalable synthesis was developed for the preparation of oxadiazole based S1P1 inhibitors. A new method for the separation of triphenylphosphine oxide from reaction products and an improved method for the synthesis of oxadiazoles in the presence of DBU were incorporated into the process to achieve its scalability.
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