Is the Change of Integrin αvβ3 Expression in the Infarcted Myocardium Related to the Clinical Outcome?

Two adult male patients with myocardial infarction underwent Ga-BNOTA-PRGD2 (arginine-glycine-aspartic acid [RGD]) PET/CT scans. The initial images that were acquired within 1 week after the cardiac event showed RGD retention in the infarcted regions in both patients. At follow-up Ga-BNOTA-PRGD2 PET/CT scans, RGD uptake was again noticed in the infracted region in the patient who was still had symptoms. However, in the patient who had become asymptomatic, RGD uptake in the infarcted region was no longer visualized.