亲爱的研友该休息了!由于当前在线用户较少,发布求助请尽量完整地填写文献信息,科研通机器人24小时在线,伴您度过漫漫科研夜!身体可是革命的本钱,早点休息,好梦!

The future of pharmacogenetics in Parkinson's disease treatment

梅德林 医学 精神科 图书馆学 计算机科学 生物 生物化学
作者
Mara H. Hutz,Carlos Roberto de Mello Rieder
出处
期刊:Pharmacogenomics [Future Medicine]
卷期号:19 (3): 171-174 被引量:2
标识
DOI:10.2217/pgs-2017-0180
摘要

PharmacogenomicsVol. 19, No. 3 EditorialThe future of pharmacogenetics in Parkinson's disease treatmentMara H Hutz & Carlos RM RiederMara H Hutz*Author for correspondence: Tel.: +55 51 3308 6720; Fax: +55 51 3308 7311; E-mail Address: mara.hutz@ufrgs.br Departamento de Genética, Instituto de Biociências, Universidade Federal do Rio Grande do Sul, Porto Alegre, 91501-970, Brazil & Carlos RM Rieder Serviço de Neurologia, Hospital de Clínicas de Porto Alegre, Porto Alegre, 90035-903, BrazilPublished Online:1 Dec 2017https://doi.org/10.2217/pgs-2017-0180AboutSectionsView ArticleView Full TextPDF/EPUB ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareShare onFacebookTwitterLinkedInReddit View articleKeywords: genetic diversityParkinson's diseasepharmacogenomicsReferences1 Lees AJ, Hardy J, Revesz T. Parkinson's disease. Lancet 373, 2055–2066 (2009).Crossref, Medline, CAS, Google Scholar2 Foltynie T, Brayne C, Barker RA. The heterogeneity of idiopathic Parkinson's disease. J. Neurol. 249, 138–145 (2002).Crossref, Medline, Google Scholar3 Marras C, Lang A. Parkinson's disease subtypes: lost in translation? J. Neurol. Neurosurg. Psychiatry 84, 409–415 (2013).Crossref, Medline, Google Scholar4 Thenganatt MA, Jankovic J. Parkinson disease subtypes. JAMA Neurol. 7, 499–504 (2014).Crossref, Google Scholar5 Riedel O, Bitters D, Amann U, Garbe E, Langner I. Estimating the prevalence of Parkinson's disease (PD) and proportions of patients with associated dementia and depression among the older adults based on secondary claims data. Int. J. Geriatr. Psychiatry 31, 938–943 (2016).Crossref, Medline, CAS, Google Scholar6 Hirsch L, Jette N, Frolkis A, Steeves T, Pringsheim T. The incidence of Parkinson's disease: a systematic review and meta-analysis. Neuroepidemiology 46, 292–300 (2016).Crossref, Medline, Google Scholar7 Pringsheim T, Jette N, Frolkis A, Steeves TD. The prevalence of Parkinson's disease: a systematic reviewand meta-analysis. Mov. Disord. 29, 1583–1590 (2014).Crossref, Medline, Google Scholar8 Cacabelos R. Parkinson's disease: from pathogenesis to pharmacogenomics. Int. J. Mol. Sci. 18(3), pii:E551 (2017).Crossref, Google Scholar9 Ahlskog JE, Muenter MD. Frequency of levodopa-related dyskinesias and motor fluctuations as estimated from the cumulative literature. Mov. Disord. 16(3), 448–458 (2001).Crossref, Medline, CAS, Google Scholar10 Sharma JC, Bachmann CG, Linazasoro G. Classifying risk factors for dyskinesia in Parkinson's disease. Parkinsonism Relat. Disord. 16(8), 490–497 (2010).Crossref, Medline, CAS, Google Scholar11 Rieck M, Schumacher-Schuh AF, Altmann V et al. DRD2 haplotype is associated with dyskinesia induced by levodopa therapy in Parkinson's disease patients. Pharmacogenomics 13, 1701–1710 (2012).Link, CAS, Google Scholar12 Factor SA. Current status of symptomatic medical therapy in Parkinson's disease. Neurotherapeutics 5, 164–180 (2008).Crossref, Medline, CAS, Google Scholar13 Kalinderi K, Fidani L, Katsarou Z, Bostantjopoulou S. Pharmacological treatment and the prospect of pharmacogenetics in Parkinson's disease. 65, 1289–1294 (2011).Crossref, Google Scholar14 Schumacher-Schuh AF, Rieder CR, Hutz MH. Parkinson's disease pharmacogenomics: new findings and perspectives. Pharmacogenomics 15, 1253–1271 (2014).Link, CAS, Google Scholar15 Payami H, Factor SA. Promise of pharmacogenomics for drug discovery, treatment and prevention of Parkinson's disease. A perspective. Neurotherapeutics 11, 111–116 (2014).Crossref, Medline, CAS, Google Scholar16 Payami H. The emerging science of precision medicine and pharmacogenomics for Parkinson's disease. Mov. Disord. 32, 1139–1146 (2017).Crossref, Medline, Google Scholar17 Hill-Burns EM, Debelius JW, Wissemann WT et al. Parkinson's disease and Parkinson's disease medications have distinct signatures of the gut microbiome. Mov. Disord. 32, 739–749 (2017).Crossref, Medline, CAS, Google Scholar18 Bu LL, Yang K, Xiong WX et al. Toward precision medicine in Parkinson's disease. Ann. Transl. Med. 4(2), 26 (2016).Medline, Google Scholar19 von Coelln R, Shulman LM. Clinical subtypes and genetic heterogeneity: of lumping and splitting in Parkinson's disease. Curr. Opin. Neurol. 29, 727–734 (2016).Crossref, Medline, CAS, Google ScholarFiguresReferencesRelatedDetailsCited ByPharmacogenetic profile and the development of the dyskinesia induced by levodopa-therapy in Parkinson's disease patients: a population-based cohort study5 November 2020 | Molecular Biology Reports, Vol. 47, No. 11Cellular and Molecular Aspects of Parkinson Treatment: Future Therapeutic Perspectives5 November 2018 | Molecular Neurobiology, Vol. 56, No. 7 Vol. 19, No. 3 Follow us on social media for the latest updates Metrics Downloaded 252 times History Received 2 November 2017 Accepted 3 November 2017 Published online 1 December 2017 Published in print February 2018 Information© 2018 Future Medicine LtdKeywordsgenetic diversityParkinson's diseasepharmacogenomicsFinancial & competing interests disclosureMH Hutz and CRM Rieder are funded by grants from Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq, Brazil) and Coordenação de Pessoal de Nývel Superior (CAPES, Brazil). The authors have no other relevant affiliations or financial involvement with any organization or entity with a financial interest in or financial conflict with the subject matter or materials discussed apart from those disclosed.No writing assistance was utilized in the production of this manuscript.PDF download
最长约 10秒,即可获得该文献文件

科研通智能强力驱动
Strongly Powered by AbleSci AI
更新
PDF的下载单位、IP信息已删除 (2025-6-4)

科研通是完全免费的文献互助平台,具备全网最快的应助速度,最高的求助完成率。 对每一个文献求助,科研通都将尽心尽力,给求助人一个满意的交代。
实时播报
89完成签到,获得积分10
刚刚
追寻绮玉完成签到,获得积分10
2秒前
SiboN发布了新的文献求助10
2秒前
yuan完成签到,获得积分10
7秒前
wangermazi完成签到,获得积分0
18秒前
田様应助玖生采纳,获得10
19秒前
22秒前
梁33完成签到,获得积分10
27秒前
cccttt发布了新的文献求助10
27秒前
激动的55完成签到 ,获得积分10
33秒前
米其林完成签到,获得积分10
38秒前
43秒前
桐桐应助lililili采纳,获得10
44秒前
李桂芳发布了新的文献求助10
48秒前
55秒前
zly完成签到 ,获得积分10
58秒前
lililili发布了新的文献求助10
1分钟前
CipherSage应助阿迪采纳,获得10
1分钟前
1分钟前
vicky完成签到 ,获得积分10
1分钟前
redstone完成签到,获得积分10
1分钟前
阿迪发布了新的文献求助10
1分钟前
研友_VZG7GZ应助xuj1245采纳,获得10
1分钟前
qiuyu发布了新的文献求助10
1分钟前
酷波er应助SiboN采纳,获得10
1分钟前
1分钟前
米其林发布了新的文献求助20
1分钟前
阿迪完成签到,获得积分20
1分钟前
小蛇玩完成签到,获得积分10
1分钟前
李桂芳发布了新的文献求助10
1分钟前
无语的诗柳完成签到 ,获得积分10
1分钟前
科研通AI5应助科研通管家采纳,获得10
1分钟前
科研通AI2S应助科研通管家采纳,获得10
1分钟前
田様应助科研通管家采纳,获得10
1分钟前
1分钟前
称心妙竹应助科研通管家采纳,获得20
1分钟前
1分钟前
韧战发布了新的文献求助10
1分钟前
顾矜应助LL采纳,获得10
1分钟前
去小岛上流浪完成签到,获得积分10
1分钟前
高分求助中
Pipeline and riser loss of containment 2001 - 2020 (PARLOC 2020) 1000
Comparing natural with chemical additive production 500
Machine Learning in Chemistry 500
Phylogenetic study of the order Polydesmida (Myriapoda: Diplopoda) 500
A Manual for the Identification of Plant Seeds and Fruits : Second revised edition 500
The Social Work Ethics Casebook: Cases and Commentary (revised 2nd ed.) 400
Refractory Castable Engineering 400
热门求助领域 (近24小时)
化学 医学 生物 材料科学 工程类 有机化学 内科学 生物化学 物理 计算机科学 纳米技术 遗传学 基因 复合材料 化学工程 物理化学 病理 催化作用 免疫学 量子力学
热门帖子
关注 科研通微信公众号,转发送积分 5198303
求助须知:如何正确求助?哪些是违规求助? 4379340
关于积分的说明 13637951
捐赠科研通 4235367
什么是DOI,文献DOI怎么找? 2323346
邀请新用户注册赠送积分活动 1321439
关于科研通互助平台的介绍 1272342