医学
失血
血液管理
止血
围手术期
外科
麻醉
输血
氨甲环酸
抗纤维溶解
止血剂
重症监护医学
作者
Jesse E. Bible,Muhammad Z. Mirza,Mark A. Knaub
出处
期刊:Journal of the American Academy of Orthopaedic Surgeons
[American Academy of Orthopaedic Surgeons]
日期:2018-01-15
卷期号:26 (2): 35-44
被引量:46
标识
DOI:10.5435/jaaos-d-16-00184
摘要
Substantial blood loss during spine surgery can result in increased patient morbidity and mortality. Proper preoperative planning and communication with the patient, anesthesia team, and operating room staff can lessen perioperative blood loss. Advances in intraoperative antifibrinolytic agents and modified anesthesia techniques have shown promising results in safely reducing blood loss. The surgeon’s attention to intraoperative hemostasis and the concurrent use of local hemostatic agents also can lessen intraoperative bleeding. Conversely, the use of intraoperative blood salvage has come into question, both for its potential inability to reduce the need for allogeneic transfusions as well as its cost-effectiveness. Allogeneic blood transfusion is associated with elevated risks, including surgical site infection. Thus, desirable transfusion thresholds should remain restrictive.
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