干细胞
羊膜上皮细胞
胚胎干细胞
细胞生物学
生物
间充质干细胞
诱导多能干细胞
羊膜干细胞
免疫学
成体干细胞
细胞疗法
细胞分化
羊水
多能干细胞
干细胞疗法
细胞
电池类型
祖细胞
胎儿
怀孕
生物化学
遗传学
基因
摘要
Multiple stem cell types can be isolated from the human placenta. Recent advances in stem cell biology have revealed that human amniotic epithelial cells (hAECs) are one of the perinatal stem cells which possess embryonic stem cell-like differentiation capability and adult stem cell-like immunomodulatory properties. Unlike other types of placental stem cells, hAECs are derived from pluripotent epiblasts and maintain multilineage differentiation potential throughout gestation. Similar to mesenchymal stem cells, hAECs are also able to modulate the local immune response. These, and other properties, make hAECs attractive for cellular therapy. This review article summarizes current knowledge of stem cell characteristics and immunomodulatory properties of amniotic epithelial cells and aims to advance our understanding towards the goal of novel therapy development.
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