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MS-based approaches for studying the pharmacokinetics of protein drugs

图书馆学 梅德林 计算机科学 化学 生物化学
作者
Cédric Mesmin,François Fenaille,Éric Ezan,François Bécher
出处
期刊:Bioanalysis [Newlands Press Ltd]
卷期号:3 (5): 477-480 被引量:33
标识
DOI:10.4155/bio.11.21
摘要

BioanalysisVol. 3, No. 5 EditorialMS-based approaches for studying the pharmacokinetics of protein drugsCédric Mesmin, François Fenaille, Eric Ezan & François BecherCédric MesminCEA, iBiTec-S, Service de Pharmacologie et d'Immunoanalyse, 91191 Gif-sur-Yvette, France. , François FenailleCEA, iBiTec-S, Service de Pharmacologie et d'Immunoanalyse, 91191 Gif-sur-Yvette, France. , Eric EzanCEA, Ibeb, Biochemistry and Nuclear Toxicology Research Unit, Marcoule, France. & François Becher† Author for correspondenceCEA, iBiTec-S, Service de Pharmacologie et d'Immunoanalyse, 91191 Gif-sur-Yvette, France. Published Online:9 Mar 2011https://doi.org/10.4155/bio.11.21AboutSectionsView ArticleView Full TextPDF/EPUB ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareShare onFacebookTwitterLinkedInReddit View articleKeywords: biologicsbiotherapeuticsMSpharmacokineticsproteinBibliography1 Chen G, Warrack BM, Goodenough AK, Wei H, Wang-Iverson DB, Tymiak AA. 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Life Sci.837(1–2),49–58 (2006).Crossref, Medline, Google ScholarFiguresReferencesRelatedDetailsCited ByEnrichment of protein therapeutics and biomarkers for LC–MS quantificationJie Pu, Bo An, Faye Vazvaei & Jun Qu4 July 2018 | Bioanalysis, Vol. 10, No. 13LC–MS/MS strategies for therapeutic antibodies and investigation into the quantitative impact of antidrug-antibodiesMatthew Ewles, Ranbir Mannu, Chris Fox, Johannes Stanta, Graeme Evans, Lee Goodwin, James Duffy, Len Bell, Sian Estdale & David Firth25 November 2016 | Bioanalysis, Vol. 8, No. 24Quantitative MS analysis of therapeutic mAbs and their glycosylation for pharmacokinetics study10 December 2015 | PROTEOMICS - Clinical Applications, Vol. 10, No. 4Quantitation of a PEGylated protein in monkey serum by UHPLC-HRMS using a surrogate disulfide-containing peptide: A new approach to bioanalysis and in vivo stability evaluation of disulfide-rich protein therapeuticsAnalytica Chimica Acta, Vol. 916LC–MS/MS multiplexed assay for the quantitation of a therapeutic protein BMS-986089 and the target protein MyostatinYongxin Zhu, Celia D'Arienzo, Zhen Lou, Alexander Kozhich, Malavi Madireddi, Anjaneya Chimalakonda, Adrienne Tymiak & Timothy V Olah26 January 2016 | Bioanalysis, Vol. 8, No. 3Cutting-edge mass spectrometry methods for the multi-level structural characterization of antibody-drug conjugates22 January 2016 | Expert Review of Proteomics, Vol. 13, No. 2Validated LC/MS Bioanalysis of Rituximab CDR Peptides Using Nano-surface and Molecular-Orientation Limited (nSMOL) ProteolysisBiological & Pharmaceutical Bulletin, Vol. 39, No. 7MS-based protein quantification in a discovery setting24 October 2014Generic Automated Method for Liquid Chromatography–Multiple Reaction Monitoring Mass Spectrometry Based Monoclonal Antibody Quantitation for Preclinical Pharmacokinetic Studies14 August 2014 | Analytical Chemistry, Vol. 86, No. 17Assessment of the metabolism of therapeutic proteins and antibodies4 June 2014 | Expert Opinion on Drug Metabolism & Toxicology, Vol. 10, No. 8Guanidinated protein internal standard for immunoaffinity-liquid chromatography/tandem mass spectrometry quantitation of protein therapeutics22 May 2014 | Rapid Communications in Mass Spectrometry, Vol. 28, No. 13Development of a highly sensitive liquid chromatography/tandem mass spectrometry method to quantify total and free levels of a target protein, interferon-gamma-inducible protein-10, at picomolar levels in human serum23 May 2014 | Rapid Communications in Mass Spectrometry, Vol. 28, No. 13Application of high-resolution MS in the quantification of a therapeutic monoclonal antibody in human plasmaKevork Mekhssian, Jean-Nicholas Mess & Fabio Garofolo26 August 2014 | Bioanalysis, Vol. 6, No. 13Quantitation of human peptides and proteins via MS: review of analytically validated assaysDerek L Chappell, Michael E Lassman, Thomas McAvoy, Mingxiang Lin, Daniel S Spellman, Omar F Laterza26 August 2014 | Bioanalysis, Vol. 6, No. 13LC–MS/MS quantification of next-generation biotherapeutics: a case study for an IgE binding Nanobody in cynomolgus monkey plasmaKoen Sandra, Kjell Mortier, Lucie Jorge, Luis C Perez, Pat Sandra, Sofie Priem, Sofie Poelmans & Marie-Paule Bouche20 June 2014 | Bioanalysis, Vol. 6, No. 9Bioanalytical Methods and Immunogenicity Assays14 March 2014Application and challenges in using LC–MS assays for absolute quantitative analysis of therapeutic proteins in drug discoveryJoanna Zheng, John Mehl, Yongxin Zhu, Baomin Xin & Timothy Olah4 April 2014 | Bioanalysis, Vol. 6, No. 6Modern chromatographic and mass spectrometric techniques for protein biopharmaceutical characterizationJournal of Chromatography A, Vol. 1335Bioanalysis of therapeutic peptides: Differentiating between total and anti-drug antibody bound drug using liquid chromatography–tandem mass spectrometry quantitationJournal of Chromatography A, Vol. 1316Best Practices in Biological Sample Preparation for LC-MS Bioanalysis30 August 2013Pharmacokinetic studies of protein drugs: Past, present and futureAdvanced Drug Delivery Reviews, Vol. 65, No. 8MS-based approaches to unravel the molecular complexity of proprotein-derived biomarkers and support their quantification: the examples of B-type natriuretic peptide and apelin peptidesCédric Mesmin, Margaux Renvoisé, François Becher, Eric Ezan & François Fenaille5 December 2012 | Bioanalysis, Vol. 4, No. 23Clinical Pharmacokinetic Assessment of an Anti-MAdCAM Monoclonal Antibody Therapeutic by LC-MS/MS5 July 2012 | Analytical Chemistry, Vol. 84, No. 14A universal surrogate peptide to enable LC-MS/MS bioanalysis of a diversity of human monoclonal antibody and human Fc-fusion protein drug candidates in pre-clinical animal studies24 May 2012 | Biomedical Chromatography, Vol. 9Mass spectrometric quantification of AcSDKP-NH2 in human plasma and urine and comparison with an immunoassay8 December 2011 | Rapid Communications in Mass Spectrometry, Vol. 26, No. 2Pellet digestion: a simple and efficient sample preparation technique for LC–MS/MS quantification of large therapeutic proteins in plasmaZheng Ouyang, Michael T Furlong, Steven Wu, Bogdan Sleczka, James Tamura, Haiqing Wang, Suzanne Suchard, Anish Suri, Timothy Olah, Adrienne Tymiak & Mohammed Jemal23 December 2011 | Bioanalysis, Vol. 4, No. 1Quantitation of therapeutic proteins following direct trypsin digestion of dried blood spot samples and detection by LC–MS-based bioanalytical methods in drug discoveryBogdan G Sleczka, Celia J D'Arienzo, Adrienne A Tymiak & Timothy V Olah23 December 2011 | Bioanalysis, Vol. 4, No. 1Metabolism of biologics: biotherapeutic proteinsLora L Hamuro & Narendra S Kishnani17 January 2012 | Bioanalysis, Vol. 4, No. 2Differences in bioanalytical method validation for biologically derived macromolecules (biosimilars) compared with small molecules (generics)Philip Oldfield14 July 2011 | Bioanalysis, Vol. 3, No. 14 Vol. 3, No. 5 Follow us on social media for the latest updates Metrics Downloaded 975 times History Published online 9 March 2011 Published in print March 2011 Information© Future Science LtdKeywordsbiologicsbiotherapeuticsMSpharmacokineticsproteinFinancial & competing interests disclosureThe authors have no relevant affiliations or financial involvement with any organization or entity with a financial interest in or financial conflict with the subject matter or materials discussed in the manuscript. This includes employment, consultancies, honoraria, stock ownership or options, expert testimony, grants or patents received or pending, or royalties. No writing assistance was utilized in the production of this manuscript.PDF download

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