干细胞
造血
病毒载体
生物
癌症研究
转导(生物物理学)
病毒学
细胞生物学
遗传学
基因
重组DNA
生物化学
作者
Cathy X. Wang,Blythe Sather,Xuefeng Wang,Jennifer E. Adair,Iram Khan,Swati Singh,Shanshan Lang,Amie B. Adams,Gabrielle Curinga,Hans‐Peter Kiem,Carol H. Miao,David J. Rawlings,Bruce E. Torbett
出处
期刊:Blood
[American Society of Hematology]
日期:2014-08-07
卷期号:124 (6): 913-923
被引量:73
标识
DOI:10.1182/blood-2013-12-546218
摘要
Key Points Rapamycin significantly enhances lentiviral vector gene delivery to hematopoietic stem cells while preserving engraftment potential. Rapamycin-mediated transduction enhancement is not accompanied by alterations in lentiviral integration profile.
科研通智能强力驱动
Strongly Powered by AbleSci AI