化学
区域选择性
芳基
阳离子聚合
氢化物
还原(数学)
药物化学
限制
组合化学
有机化学
催化作用
烷基
氢
工程类
机械工程
数学
几何学
作者
Makoto N. Masuno,Tadeusz F. Molinski
标识
DOI:10.1016/s0040-4039(01)01780-4
摘要
2-Aryl-1-N-carboalkoxyenamines (enamides) are selectively reduced to the corresponding 2-arylethylamine carbamates by Et3SiH in the presence of CF3COOH in excellent yields. The reduction proceeds by addition of hydride at C-1 and the rate-limiting step involves proton transfer from CF3COOH. This reduction is useful for preparation of isotopically labeled arylethylamines.
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