Peripheral T-cell lymphomas: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up

The present guidelines cover the systemic subtypes of primary nodal and primary extranodal peripheral T-cell lymphomas (PTCLs). ESMO guidelines for primary cutaneous T-cell lymphomas are published separately [1]. Primary leukaemic PTCL subtypes (i.e. T-cell prolymphocytic leukaemia, T-cell large granular lymphocytic leukaemia, adult T-cell leukaemia/lymphoma and aggressive NK-cell leukaemia) are not covered by the present guidelines. Primary nodal PTCLs include PTCL-not otherwise specified (PTCL-NOS), anaplastic large-cell lymphoma (ALCL), both fusion protein ALCL anaplastic lymphoma kinase positive (ALCL ALK+) and ALCL anaplastic lymphoma kinase negative (ALCL ALK-), and angioimmunoblastic T-cell lymphoma (AITL).