Influential Determinants on Health-Related Quality of Life in Intensive Care Unit Survivors: A Meta-Analysis

This study aimed to identify the factors influencing the health-related quality of life (HRQoL) in ICU survivors. The electronic search period was established until April 2023, using CNKI, Wanfang, VIP, CBM, PubMed, Embase, and Cochrane databases. Meta-analysis of data was performed using RevMan 5.4 and STATA 15.0 software. Of the 183 references screened, 12 studies with a total sample size of 19,517 were eventually included. The results showed that duration of mechanical ventilation (OR = 2.24), length of stay in ICU, and length of hospital stay were risk factors for lower quality of life in ICU survivors. Gender was not associated with the quality of life of ICU survivors. The relationship between age, complication count, and quality of life of ICU survivors was not clear. Depression score had a significant effect on the mental health score (MCS) of ICU survivors. Key Words: Intensive care unit (ICU), Survivors, Health-related quality of life (HRQoL), Risk factors, Meta-analysis, Systematic review.