Neuroplasticity of the white matter tracts underlying recovery of diarrhea-predominant irritable bowel syndrome following acupuncture treatment

肠易激综合征 扣带回(脑) 白质 神经可塑性 医学 针灸科 内科学 丘脑 海马体 扣带回前部 焦虑 萧条(经济学) 腹泻 胃肠病学 心理学 精神科 磁共振成像 病理 认知 部分各向异性 放射科 替代医学 宏观经济学 经济
作者
Jing Li,WingYi Ng,Yongkang Liu,Xiaokun Fang,Zhongqiu Wang,Lixia Pei,Xuehu Wei
出处
期刊:Frontiers in Neuroscience [Frontiers Media]
卷期号:18
标识
DOI:10.3389/fnins.2024.1383041
摘要

Irritable bowel syndrome (IBS) is a functional bowel disorder frequently associated with other pain syndromes and psychiatric conditions, including depression and anxiety. These abnormalities coincide with alterations in the brain’s structure, particularly in the thalamus and cingulate system. Acupuncture has been demonstrated to be highly effective in treating IBS. However, it remains unclear how white matter (WM) tracts change after acupuncture treatment, and whether the neuroplasticity of these tracts can serve as a neural marker to assist in the development of novel treatments. In this study, we aim to answer these questions by investigating longitudinal changes in the WM of the thalamus and cingulate system in a group of diarrhea-predominant irritable bowel syndrome (IBS-D) patients before and after acupuncture treatment. We found that after acupuncture treatment, as IBS symptoms improved, there were significant changes in the microstructure of the right thalamus radiation (TR) ( p < 0.05) and the right cingulum hippocampus (CH) ( p < 0.05). At the same time, patients with reduced IBS symptom severity scores (SSSs) were associated with the change of the right CH ( p = 0.015, r = −0.491), while reduced depressive conditions correlated with the change of the left TR ( p = 0.019, r = 0.418). In addition, the consequences for the quality of life (QOL) showed a correlation with the right cingulum [cingulate cortex (CC)] ( p = 0.012, r = 0.504) and left TR ( p = 0.027, r = −0.397). Our study highlighted the potential implications of neuroplasticity in WM tracts for IBS. Furthermore, these findings suggested that the right CH, TR, and right CC can serve as potential “biomarkers” of IBS-D recovery under acupuncture treatments.
最长约 10秒,即可获得该文献文件

科研通智能强力驱动
Strongly Powered by AbleSci AI
更新
PDF的下载单位、IP信息已删除 (2025-6-4)

科研通是完全免费的文献互助平台,具备全网最快的应助速度,最高的求助完成率。 对每一个文献求助,科研通都将尽心尽力,给求助人一个满意的交代。
实时播报
李洪晔发布了新的文献求助10
1秒前
2秒前
zyw发布了新的文献求助10
2秒前
ws340822发布了新的文献求助10
3秒前
xx完成签到,获得积分10
3秒前
王科研完成签到 ,获得积分10
3秒前
筋筋子完成签到,获得积分10
3秒前
3秒前
科研小虫发布了新的文献求助10
4秒前
sen完成签到,获得积分10
4秒前
Zzz发布了新的文献求助10
5秒前
ly发布了新的文献求助10
5秒前
5秒前
江筱筱完成签到,获得积分10
5秒前
Jasper应助ccl采纳,获得10
6秒前
6秒前
慕青应助xx采纳,获得10
6秒前
可爱的函函应助叁月二采纳,获得10
6秒前
iNk应助404医学狗采纳,获得20
7秒前
7秒前
8秒前
早日毕业发布了新的文献求助10
8秒前
干羞花完成签到,获得积分10
8秒前
9秒前
9秒前
9秒前
10秒前
阿落落呀发布了新的文献求助10
10秒前
orixero应助lisier采纳,获得50
11秒前
11秒前
在水一方应助xutong de采纳,获得10
11秒前
阿鸢完成签到,获得积分10
11秒前
11秒前
天天快乐应助Teresa采纳,获得10
11秒前
核桃应助xueerbx采纳,获得10
12秒前
12秒前
13秒前
爱情哈尔发布了新的文献求助10
13秒前
_11_发布了新的文献求助10
13秒前
Kbobo发布了新的文献求助30
14秒前
高分求助中
The Mother of All Tableaux: Order, Equivalence, and Geometry in the Large-scale Structure of Optimality Theory 3000
A new approach to the extrapolation of accelerated life test data 1000
北师大毕业论文 基于可调谐半导体激光吸收光谱技术泄漏气体检测系统的研究 390
Phylogenetic study of the order Polydesmida (Myriapoda: Diplopoda) 370
Robot-supported joining of reinforcement textiles with one-sided sewing heads 360
Atlas of Interventional Pain Management 300
Novel Preparation of Chitin Nanocrystals by H2SO4 and H3PO4 Hydrolysis Followed by High-Pressure Water Jet Treatments 300
热门求助领域 (近24小时)
化学 材料科学 医学 生物 工程类 有机化学 生物化学 物理 内科学 纳米技术 计算机科学 化学工程 复合材料 遗传学 基因 物理化学 催化作用 冶金 细胞生物学 免疫学
热门帖子
关注 科研通微信公众号,转发送积分 4011501
求助须知:如何正确求助?哪些是违规求助? 3551133
关于积分的说明 11307791
捐赠科研通 3285391
什么是DOI,文献DOI怎么找? 1811040
邀请新用户注册赠送积分活动 886767
科研通“疑难数据库(出版商)”最低求助积分说明 811636