Stille反应
化学
试剂
芳基
卤化物
偶联反应
催化作用
聚合物
硅胶
钯
卤代芳基
有机化学
高分子化学
组合化学
烷基
作者
Jacques R. Chrétien,Aurélie Mallinger,Françoise Zammattio,Erwan Le Grognec,Michaël Paris,Gilles Montavon,Jean‐Paul Quintard
标识
DOI:10.1016/j.tetlet.2007.01.028
摘要
The synthesis of two new vinyltin reagents grafted on an insoluble macroporous polymer is reported. These reagents were used in the palladium-catalyzed Stille cross-coupling reaction with aryl halides. In all reactions, the conversion of the starting aryl halide is high and the amount of organotin by-product is particularly low (at the end of the catalytic run, the amount of Sn is up to 16 ppm in the crude reaction mixture removed of the insoluble polymer, and it is less than 1 ppm in the product purified by chromatography on silica gel).
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