医学
视神经
颅内压
阶段(地层学)
急性中风
冲程(发动机)
前瞻性队列研究
核医学
眼科
放射科
外科
内科学
机械工程
古生物学
组织纤溶酶原激活剂
工程类
生物
作者
David Školoudík,Roman Herzig,Táňa Fadrná,Michal Bar,Pavel Hradílek,Martin Roubec,Monika Jelínková,Daniel Šaňák,Michal Král,Jana Chmelová,Miroslav Herman,Kateřina Langová,Petr Kaňovský
标识
DOI:10.1136/bjo.2009.172890
摘要
Aims
Optic nerve sheath diameter (ONSD) enlargement is detectable in patients with increased intracranial pressure. The aim was to detect an enlargement of the ONSD using optic nerve sonography in patients with acute intracerebral haemorrhage (ICH) within 6 h of the onset of symptoms. Methods
Thirty-one acute ICH patients, 15 age-matched acute ischaemic stroke patients and 16 age-matched healthy volunteers were enrolled consecutively in this prospective bi-centre observational study. All acute stroke patients underwent brain CT, optic nerve sonography and transcranial colour-coded duplex sonography (TCCS) at admission within 6 h of stroke onset. The ONSD both 3.0 and 12.0 mm behind the globe using optic nerve sonography were recorded and statistically evaluated, as were age, sex, haemorrhage volume and midline shift measured by CT, and blood flow velocities in both middle cerebral arteries using TCCS. Results
In acute ICH patients, a significant enlargement of ONSD was detected (p<0.0083). The best cut-off point to predict ICH volume >2.5 cm3 was the relative ONSD enlargement of >0.66 mm (>21 %), with 90.3% accuracy and kappa coefficient 0.760 (95% CI 0.509 to 1.000). Conclusions
Sonographically measured enlargement of the ONSD may already be detectable in the hyperacute stage of increased intracranial pressure.
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