纠纷
痴呆
疾病
神经纤维缠结
淀粉样蛋白(真菌学)
神经科学
阿尔茨海默病
τ蛋白
BETA(编程语言)
β淀粉样蛋白
医学
心理学
化学
老年斑
病理
计算机科学
程序设计语言
纯数学
数学
作者
Hossein Ashrafian,Elaheh Hadi Zadeh,Rizwan Hasan Khan
标识
DOI:10.1016/j.ijbiomac.2020.11.192
摘要
It is reported that approximately 40 million people are suffering from dementia, globally. Dementia is a group of symptoms that affect neurons and cause some mental disorders, such as losing memory. Alzheimer's disease (AD) which is known as the most common cause of dementia, is one of the top medical care concerns across the world. Although the exact sources of the disease are not understood, is it believed that aggregation of amyloid-beta (Aβ) outside of neuron cells and tau aggregation or neurofibrillary tangles (NFTs) formation inside the cell may play crucial roles. In this paper, we are going to review studies that targeted inhibition of amyloid plaque and tau protein tangle formation, to suppress or postpone AD.
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